Antibody-antigen kinetics constrain intracellular humoral immunity
نویسندگان
چکیده
منابع مشابه
Antibody-antigen kinetics constrain intracellular humoral immunity
During infection with non-enveloped viruses, antibodies stimulate immunity from inside cells by activating the cytosolic Fc receptor TRIM21. This intracellular humoral response relies on opsonized viral particles reaching the cytosol intact but the antigenic and kinetic constraints involved are unknown. We have solved the structure of a potent TRIM21-dependent neutralizing antibody in complex w...
متن کاملCorrigendum: Antibody-antigen kinetics constrain intracellular humoral immunity
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2016
ISSN: 2045-2322
DOI: 10.1038/srep37457